据最新的全国调查显示,中国18岁及以上的人群中,糖尿病的患病率高达11.2%。如果糖尿病患者的血糖长期无法有效控制,可能会诱发脑血管并发症。糖尿病会导致有害负氧离子的积累,从而使糖尿病患者发生出血性脑病的风险提高了1.5倍。 而在最近的一项研究中,广西医科大学第一附属医院的科研团队在《欧洲生物化学学会开放期刊》(FEBS Open Bio)上公布了他们的最新研究。
[1] https://www.nmn999.com[2] Liy, Teng D, ShiX, et al. Prevalence of diabetes recorded in mainland China using 2018 diagnostic criteria from theAmerican Diabetes Association: national cross sectional study. BMJ. 2020: 369. doi: https://doiorg/10.1136/bmj.m997(Published 28 April 2020[3] Umemura T, Kawamura T and Hotta N. Pathogenesis and neuroimaging of cerebral large and small vessel disease in type2 diabetes: a possible link between cerebral and retinal microvascular abnormalities. J Diabet lnvestigat. 2019, 8,134-148.[4] Deng X, Liang X, Yang H,et al. Nicotinamide mononucleotide (NMN) protects bEnd.3 cells against H202 - induceddamage via NAMPT and the NF - KB p65 signalling pathway. FEBS Open Bio. 2020. Accepted Author Manuscript. D0:10.1002/2211-5463.13067